| 发明名称 |
CYCLODEXTRIN |
| 摘要 |
The invention provides a method for preparing sulphoalkyl ether-β-cyclodextrin. The method comprises first contacting cyclodextrin with a base to form activated cyclodextrin. The method then comprises separately contacting the activated cyclodextrin with an alkyl sultone to form sulphoalkyl ether-β-cyclodextrin. The activation reaction is carried in batch and the sulphoalkylation reaction is carried out under continuous flow conditions. |
| 申请公布号 |
US2015025023(A1) |
申请公布日期 |
2015.01.22 |
| 申请号 |
US201414333417 |
申请日期 |
2014.07.16 |
| 申请人 |
The University of Greenwich ;Curadev Pharma Pvt Ltd |
发明人 |
Savage Tammy;Wicks Stephen;Mitchell John |
| 分类号 |
C08B37/16;A61K31/506;A61K45/06;A61K47/40 |
主分类号 |
C08B37/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preparing sulphoalkyl ether-β-cyclodextrin, the method comprising contacting cyclodextrin with a base to form activated cyclodextrin, and separately contacting the activated cyclodextrin with an alkyl sultone to form sulphoalkyl ether-β-cyclodextrin, characterised in that the sulphoalkylation reaction is carried out under continuous flow conditions. |
| 地址 |
London GB |
