发明名称 PHENYL CARBAMATES AND THEIR USE AS INHIBITORS OF THE FATTY ACID AMIDE HYDROLASE (FAAH) ENZYME AND MODULATORS OF THE D3 DOPAMINE RECEPTOR (D3DR)
摘要 The invention provides compounds of Formula (I) or pharmaceutically acceptable salts thereof wherein Ar', R1, R2, R3, R4, X, Y are as defined in the description of invention, as multi-target directed ligands (MTDLs) that are at the same time inhibitors of the fatty acid amide hydrolase (FAAH) enzyme and modulators of the D3 dopamine receptor (D3DR), their methods of preparation, formulations and therapeutic applications thereof.
申请公布号 WO2015007615(A1) 申请公布日期 2015.01.22
申请号 WO2014EP64853 申请日期 2014.07.10
申请人 FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 BOTTEGONI, GIOVANNI;DE SIMONE, ALESSIO;RUDA, GIAN FILIPPO;CAVALLI, ANDREA;BANDIERA, TIZIANO;PIOMELLI, DANIELE
分类号 C07D209/88;A61K31/495;A61K31/496;A61P25/18;A61P25/22;A61P25/24;A61P25/30;C07D211/38;C07D213/30;C07D295/125;C07D295/13 主分类号 C07D209/88
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