| 发明名称 |
LIQUID-FILLED HARD GEL CAPSULE PHARMACEUTICAL FORMULATIONS |
| 摘要 |
Embodiments of liquid-filled hard gel capsule pharmaceutical formulations comprise a non-emulsified mixture, wherein the non-emulsified mixture comprises about 0.1 to about 5% by weight of at least one active pharmaceutical ingredient, about 50 to about 95% by weight long chain triglycerides, and about 5 to about 25% by weight medium chain mono/diglycerides, wherein the long chain triglycerides and medium chain mono/diglycerides are present at a ratio by weight of from about 10:1 to about 5:1. |
| 申请公布号 |
US2015024045(A1) |
申请公布日期 |
2015.01.22 |
| 申请号 |
US201414510699 |
申请日期 |
2014.10.09 |
| 申请人 |
Mylan Inc. |
发明人 |
Chattaraj Sarat C.;Redelman Glenn Allen |
| 分类号 |
A61K9/48;A61K31/18;A61K31/473 |
主分类号 |
A61K9/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A liquid-filled hard gel capsule pharmaceutical formulation comprising a non-emulsified mixture disposed in a hard capsule shell, wherein the non-emulsified mixture comprises:
about 0.1 to about 5% by weight of at least one active pharmaceutical ingredient; about 50 to about 95% by weight long chain triglycerides; and about 5 to about 25% by weight medium chain mono/diglycerides, wherein the long chain triglycerides and medium chain mono/diglycerides are present at a ratio by weight of from about 10:1 to about 5:1. |
| 地址 |
Morgantown WV US |
