发明名称 METHOD FOR PREPARING CORNEAL ENDOTHELIAL CELL
摘要 The present invention relates to a method for preparing corneal endothelial progenitor cells by adherent culturing a cell population isolated from corneal endothelial cell tissue at a low density by using a serum-free medium. The present invention also relates to a method for preparing corneal endothelial cells by differentiation-inducing the corneal endothelial progenitor cells obtained by the aforementioned method. According to the present invention, corneal endothelial progenitor cells can be selectively grown from a corneal tissue-derived cell population, and corneal endothelial cells obtained by inducing the corneal endothelial progenitor cells can be applied to treatment of corneal endothelial diseases. As a result, problems of corneal transplantation such as shortage of donors and occurrence of rejection can be solved.
申请公布号 EP2733201(A4) 申请公布日期 2015.01.21
申请号 EP20120815195 申请日期 2012.07.13
申请人 OSAKA UNIVERSITY 发明人 HAYASHI, RYUHEI;HARA, SUSUMU;KAGEYAMA, TOMOFUMI;NISHIDA, KOHJI
分类号 C12N5/071 主分类号 C12N5/071
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