There is provided a diagnostic reagent for use in the detection of M. bovis or M. tuberculosis infection in an animal, comprising a peptide which has an epitope from Mycobacterium bovis hypothetic protein Mb3645c (SEQ ID NO: 1) or an epitope from a polypeptide having at least 76% identity with SEQ ID NO: 1. The diagnostic reagent may be for use in the detection of M. tuberculosis infection in an animal and comprise one or more peptides each consisting of one of SEQ ID NO:1-13, or a functional variant peptide having at least 90% sequence identity to and capable of eliciting a similar immune response to SEQ ID NO:1-13.
申请公布号
EP2827149(A1)
申请公布日期
2015.01.21
申请号
EP20140188545
申请日期
2008.11.06
申请人
THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS
发明人
VORDERMEIER, HANS MARTIN;SIDDERS, BENJAMIN;STOKER, NEIL GRAHAM;EWER, KATIE