发明名称 |
METHOD FOR IDENTIFICATION OF THE SEQUENCE OF POLY(A)+RNA THAT PHYSICALLY INTERACTS WITH PROTEIN |
摘要 |
The invention relates to an in vitro method for identifying the sequence of one or more poly(A)+RNA molecules that physically interacts with protein. The present invention provides a method to define the protein-bound transcriptome under any given cellular condition, such as a disease condition or after treatment with any given substance, drug, or other cellular perturbation. The invention also relates to a method for identification of a drug target and a method for the identification of one or more biomarkers, preferably for identification of a panel of biomarkers, for any given medical condition, comprising the method of the invention. |
申请公布号 |
EP2825890(A1) |
申请公布日期 |
2015.01.21 |
申请号 |
EP20130714874 |
申请日期 |
2013.03.18 |
申请人 |
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN |
发明人 |
LANDTHALER, MARKUS;MUNSCHAUER, MATHIAS;BALTZ, ALEXANDER |
分类号 |
G01N33/58;C12N15/113;C12Q1/68 |
主分类号 |
G01N33/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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