| 发明名称 |
SELECTIVE CELL TARGETING USING ADENOVIRUS AND CHEMICAL DIMERS |
| 摘要 |
<p>Compositions and methods for retargeting adenovirus to a cell using chemical dimers are described. In particular, a recombinant adenovirus comprising a nucleic acid comprising a capsid-dimerizing agent binder conjugate and a ligand-dimerizing agent binder conjugate is provided.</p> |
| 申请公布号 |
EP2825649(A1) |
申请公布日期 |
2015.01.21 |
| 申请号 |
EP20130760608 |
申请日期 |
2013.03.13 |
| 申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
O'SHEA, CLODAGH;MIYAKE-STONER, SHIGEKI;POWERS, COLIN |
| 分类号 |
C12N15/861;A61K35/761 |
主分类号 |
C12N15/861 |
| 代理机构 |
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