Medical devices having drugs adhered to the surface thereof.

摘要

Medical devices (10) implanted or otherwise used in a mammal are made less prone to trigger adverse reactions by use of gas cluster ion-beam (GCIB) (128) surface modification and/or monometer ion beam surface modification to implant, apply, or adhere various drug molecules directly into or onto the surface of medical devices (10). This is accomplished without the need for a polymer or any other binding agent to retain the drug.