发明名称 |
TREATMENT OF IMMUNOCOMPROMISED CONDITIONS WITH E-SELECTIN ANTAGONIST AND G-CSF |
摘要 |
This invention discloses the use of an E-selectin antagonist and a mobilizer of hematopoietic stem cells or progenitor cells in methods and compositions for treating or preventing immunocompromised conditions resulting from medical treatment. The present invention is particular relevant for prophylaxis and/or treatment of hematopoietic disorders including neutropenia, agranulocytosis, anemia and thrombocytopenia in individuals receiving or proposed to receive treatments that target rapidly dividing cells or that disrupt the cell cycle or cell division. |
申请公布号 |
EP2249854(B1) |
申请公布日期 |
2015.01.21 |
申请号 |
EP20080858633 |
申请日期 |
2008.12.09 |
申请人 |
MATER MEDICAL RESEARCH INSTITUTE |
发明人 |
LEVESQUE, JEAN-PIERRE;WINKLER, INGRID |
分类号 |
A61K45/06;A61K31/00;A61K31/7004;A61K31/7016;A61K31/702;A61K31/7032;A61K31/7036;A61K31/7056;A61K38/17;A61K38/19;A61P7/06;A61P37/04 |
主分类号 |
A61K45/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|