<p>Antibodies and compositions capable of binding and, in a particular aspect, inhibiting the lysophosphatidylipase D activity of human autotaxin protein. The antibodies or are useful in detecting human autotaxin protein and treating diseases and disorders associated with unwanted lysophosphatidylipase D and the presence of lysophosphatidic acid, such as cancer and pulmonary diseases.</p>
申请公布号
EP2825199(A1)
申请公布日期
2015.01.21
申请号
EP20130760575
申请日期
2013.03.11
申请人
JANSSEN BIOTECH, INC.
发明人
MOORES, SHERI;PARDINAS, JOSE;ZIOBER, BARRY L.;CHI, ELLEN;DINH, THAI;EDAVETTAL, SUZANNE;FENTON, SANDRA;HAMEL, DAMON;ZHOU, H. MIMI