Chromatography column with large diameter end fitting openings

摘要

A column for use in chromatography, the column having a tube with a bore that can contain a packing medium captured between two porous plugs positioned at opposite ends. End fittings are attached to the tube ends, the end fittings having a duct with a duct opening having a diameter at least as large as the diameter of the tube bore which it faces. The duct opening may be positioned within a recess in spaced apart relation to the porous plugs to prevent the end fitting from contacting the plug and burnishing its surface.

主权项

1. A column for chromatography, said column comprising:
a tube having a bore therethrough, said bore having a diameter; a first porous plug located within said bore at a first end of said tube; a first fitting attached to said first end of said tube, said first fitting having a duct positioned therein, said duct having a first opening in facing relation with said first porous plug, said first opening having a diameter at least about equal to said bore diameter, said first opening being positioned within a recess in said first fitting and in spaced apart relation away from said first porous plug, said first fitting comprising a first sealing surface integrally formed therewith and surrounding said recess, a second sealing surface integrally formed with said tube and surrounding said bore at said first end of said tube, said first sealing surface contacting said second sealing surface and forming a seal between said first fitting and said tube.