发明名称 PROTEIN STABILISATION FORMULATION FREE FROM MAMMALIAN EXCIPIENTS
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions refers to pharmaceutics and medicine, and concerns protein and peptide stabilisation formulation which contains a hydrophilic polymer, a mixture of polyalcohol and sugar, wherein a weight ratio of polyalcohol to sugar makes from 2:1 to 5:1 (wt %), a detergent, and wherein the formulation is free from stabilising proteins. A composition and a kit for treating a disease or a composition caused by hyperactive cholinergic innervation of muscles or endocrine glands in a patient, and contain the above formulation and peptide, protein or a mixture thereof.EFFECT: group of inventions provides the better protein stability in the absence of stabilising proteins.13 cl, 4 ex
申请公布号 RU2539388(C2) 申请公布日期 2015.01.20
申请号 RU20110146541 申请日期 2010.04.16
申请人 MERTS FARMA GMBKH UND KO. KGAA 发明人 TEHJLOR KHAROL'D;BURGER MARKUS;MANDER GERD J.
分类号 A61K9/19;A61K38/00;A61K47/26;A61K47/30;A61K47/36 主分类号 A61K9/19
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