Dermatological compositions comprising at least one naphthoic acid compound and at least one film-forming agent and treatment of keratinization disorders therewith

摘要

Topically applicable, reduced-irritant dermatological/cosmetic compositions useful for the treatment of a variety of keratinization disorders, for example acne vulgaris, contain at least one naphthoic acid compound essentially uniformly distributed therethrough and an amount of at least one hydrophilic film-forming agent, formulated into a topically applicable, physiologically acceptable medium.

主权项

1. A topically applicable, dermatological/cosmetic gel composition useful for the treatment of acne, comprising at least one naphthoic acid compound essentially uniformly distributed therethrough, said at least one naphthoic acid compound having the formula (I): in which R is a hydrogen atom, a hydroxyl radical, a branched or unbranched alkyl radical having from 1 to 4 carbon atoms, an alkoxy radical having from 1 to 10 carbon atoms or a cycloaliphatic radical, and an amount of at least one hydrophilic film-forming agent formulated into a topically applicable, physiologically acceptable medium therefor as an aqueous gel, said aqueous gel having a pH of 5.5±0.5, wherein said at least one film-forming agent comprises copovidone.