| 发明名称 |
SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS |
| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide compounds for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.SOLUTION: This invention is directed to spiro-oxindole compounds represented by the general formula, stereoisomers, enantiomers or tautomers thereof, or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof.</p> |
| 申请公布号 |
JP2015010090(A) |
申请公布日期 |
2015.01.19 |
| 申请号 |
JP20140084287 |
申请日期 |
2014.04.16 |
| 申请人 |
XENON PHARMACEUTICALS INC |
发明人 |
CHAFEEV MIKHAIL;SULTAN CHOWDHURY;LAUREN FRASER;FU JIANMING;JONATHAN LANGILLE;SHIFENG LIU;SUN JIANYU;SUN SHAOYI;SVIRIDOV SERGUEI;WOOD MARK;ALLA ZENOVA;QI JIA;JEAN-JACQUES CADIEUX;SIMON J GAUTHIER;AMY FRANCES DOUGLAS;HSIEH TOM;CHAKKA NAGASREE;ZORAN CIKOJEVIC |
| 分类号 |
C07D491/107;A61K31/407;A61K31/41;A61K31/4155;A61K31/4178;A61K31/4184;A61K31/4192;A61K31/4196;A61K31/422;A61K31/4245;A61K31/429;A61K31/433;A61K31/437;A61K31/4439;A61K31/454;A61K31/4709;A61K31/496;A61K31/497;A61K31/499;A61K31/501;A61K31/506;A61K31/5377;A61K31/5383;A61P9/00;A61P11/00;A61P25/00;A61P25/04;A61P25/24;A61P43/00;C07D491/20;C07D491/22;C07D495/20;C07D498/20;C07D513/20;C07D513/22;C07D519/00 |
主分类号 |
C07D491/107 |
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