| 摘要 |
To provide an industrial method for producing a substituted benzoic acid compound useful as an intermediate of pharmaceutical and agricultural chemicals with high purity and high yield. A compound represented by the formula (II):
(wherein Q is a 5- or 6-membered saturated heterocyclic group (the heterocyclic group may be substituted by alkyl) containing one or two of at least one type of hetero atom selected from the group consisting of an oxygen atom and a sulfur atom, or dialkoxymethyl, T is trifluoromethyl, nitro, cyano, -SOA 1 , -SO 2 A 1 , -PO(OA 1 )(OA 2 ),-COA 1 , -CO 2 A 1 or -CONA 1 A 2 , each of A 1 and A 2 which are independent of each other, is a hydrogen atom, alkyl or haloalkyl, X is halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, dialkylaminosulfonyl, di(haloalkyl)aminosulfonyl, nitro or cyano, Y is a chlorine atom, a bromine atom or an iodine atom, and n is an integer of from 1 to 6), carbon monoxide and a compound represented by the formula R-OH (wherein R is alkyl) are reacted, followed by hydrolysis to obtain a compound represented by the formula (I):
wherein Q, T, X and n are as defined above. |
