发明名称 PHARMACEUTICAL COMPOSITION COMPRISING (1R,4R)-6'-FLUORO-N,N-DIMET HYL-4-PHENYL-4',9'-DIHYDRO-3'H-SPIRO[CYCLOHEXANE-1,1'-PYRANO [3,4,B]INDOL]-4-AMINE AND AN ANTICONVULSANT.
摘要 <p>The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient selected from (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro [cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and the physiologically acceptable salts thereof, and a second pharmacologically active ingredient which is an anticonvulsant selected from the group consisting of retigabin, lamotrigine, lacosamide, levetiracetam, carbamazepine, sultiame, phenacemide, felbamate, topiramate, pheneturide, brivaracetam, selectracetam, zonisamide, stiripentol, beclamide, mexiletin, ralfinamide, methyl- phenobarbital, phenobarbital, primidone, barbexaclone, metharbital, ethotoin, phenytoin, amino(diphenylhydantoin) valeric acid, mephenytoin, fosphenytoin, paramethadione, trimethadione, ethadione, ethosuximide, phensuximide, mesuximide, clonazepam, lorazepam, diazepam, clobazam, oxcarbazepine, eslicarbazepine, rufinamide, valproic acid, valpromide, aminobutyric acid, progabide, tiagabine, and the physiologically acceptable salts thereof.</p>
申请公布号 MX2014013179(A) 申请公布日期 2015.01.19
申请号 MX20140013179 申请日期 2013.05.16
申请人 GRÜNENTHAL GMBH 发明人 KLAUS LINZ;THOMAS CHRISTOPH;STEFANIE FROSCH
分类号 A61K31/27;A61K31/165;A61K31/4015;A61K31/407;A61K31/53;A61K31/55;A61K45/06;A61P25/08;A61P25/22;A61P29/00 主分类号 A61K31/27
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