TRICYCLIC PYRROLE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS

摘要

The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine: The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentation broth of a fungal strain Paraconiothyrium sp., or are derivatives thereof.