FORMULATIONS FOR CATHEPSIN K INHIBITORS WITH VITAMIN D

摘要

The instant invention relates to pharmaceutical compositions comprising cathespin K inhibitors and Vitamin D. The pharmaceutical compositions of the instant invention include fixed dose combinations of cathepsin K inhibitors with Vitamin D. A particularly effective cathepsin K inhibitor is N1-(l-cyanocyclopropyl)-4-fluoro-N2-{ (IS)-2,2,2-trifluoro-l-[ 4'-(methylsulfonyl)-1,1'-biphenyl-4-yl]ethyl} -L-leucinamide. Also disclosed are processes for making said pharmaceutical compositions.