发明名称 |
MEANS AND METHODS FOR ASSESSING HYPERTHYROIDISM |
摘要 |
The present invention pertains to the field of diagnostics for hyperthyroidism and toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing hyperthyroidism. It also relates to a method for determining whether a compound is capable of inducing such hyperthyroidism in a subject and to a method of identifying a drug for treating hyperthyroidism. Furthermore, the present invention relates to a device and a kit for diagnosing hyperthyroidism. |
申请公布号 |
US2015018244(A1) |
申请公布日期 |
2015.01.15 |
申请号 |
US201314379527 |
申请日期 |
2013.03.07 |
申请人 |
BASF SE |
发明人 |
Walk Tilmann B.;van Ravenzwaay Bennard;Mellert Werner;Fabian Eric;Strauss Volker;Kamp Hennicke;Wiemer Jan C.;Looser Ralf;Herold Michael Manfred;Prokoudine Alexandre |
分类号 |
G01N33/92;G01N33/70;G01N33/62;G01N33/78 |
主分类号 |
G01N33/92 |
代理机构 |
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代理人 |
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主权项 |
1. A method for diagnosing hyperthyroidism comprising:
(a) determining the amount of at least one biomarker selected from any one of Tables 1a, 1b, 2a, or 2b, in a test sample of a subject suspected to suffer from hyperthyroidism, and (b) comparing the amounts determined in step (a) to a reference, whereby hyperthyroidism is to be diagnosed. |
地址 |
Ludwigshafen DE |