发明名称 |
NOVEL CRYSTAL FORM OF DABRAFENIB MESYLATE AND PREPARATION METHOD THEREOF |
摘要 |
Disclosed are a novel crystal form of Dabrafenib mesylate and preparation method thereof. The novel crystal form of the present invention is more stable in water or an aqueous system, and has greater solubility and dissolution in water, thus having better stability and bioavailability compared with the existing crystal forms. |
申请公布号 |
WO2015003571(A1) |
申请公布日期 |
2015.01.15 |
申请号 |
WO2014CN81549 |
申请日期 |
2014.07.03 |
申请人 |
HANGZHOU PUSHAI PHARMACEUTICAL TECHNOLOGY CO., LTD. |
发明人 |
LAO, HAIPING;SHENG, XIAOXIA;SHENG, XIAOHONG |
分类号 |
C07D417/04;A61K31/506;A61P35/00 |
主分类号 |
C07D417/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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