| 发明名称 |
2-BENZYL, 3-(PYRIMIDIN-2-YL) SUBSTITUTED PYRAZOLES USEFUL AS SGC STIMULATORS |
| 摘要 |
Compound of Table I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed. |
| 申请公布号 |
US2015018353(A1) |
申请公布日期 |
2015.01.15 |
| 申请号 |
US201214368064 |
申请日期 |
2012.12.26 |
| 申请人 |
IRONWOOD PHARMACEUTICALS, INC. |
发明人 |
Kim Charles;Nakai Takashi;Moore Joel;Perl Nicholas Robert;Im G-yoon Jamie;Barden Timothy Claude;Iyengar Rajesh R.;Zimmer Daniel P.;Fretzen Angelika;Renhowe Paul Allan |
| 分类号 |
C07D403/04;A61K31/506;A61K45/06;A61K31/513;A61K31/52;C07D513/22;C07D487/04;A61K31/519;C07D473/00;C07D413/14;A61K31/4439 |
主分类号 |
C07D403/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound depicted in Table I or a pharmaceutically acceptable salt thereof. |
| 地址 |
Cambridge MA US |
