Seal Structures for Wet/Dry Automatic Injectors

摘要

An automatic injection device including a housing, a chamber with a first compartment and a second compartment, and a seal structure between the compartments. The seal structure is initially in a sealing condition that seals the first compartment from the second compartment, where the seal includes a plug and an outer sealing member. The plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment. The automatic injection device also includes a needle assembly and an activation assembly. Activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly.

主权项

1. An automatic injection device for automatically administering a medicament upon actuation thereof, the device comprising:
a housing; a chamber disposed in the housing and having a first compartment and a second compartment; a seal structure between the first compartment and the second compartment, the seal structure initially in a sealing condition that seals the first compartment from the second compartment, the seal structure comprising a plug and an outer sealing member that forms a peripheral seal with an interior wall of the chamber, wherein the plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment through the seal structure, the plug maintaining the same orientation with respect to the outer sealing member as the plug moves to convert the seal structure from the sealing condition to the mixing condition; a needle assembly connected to the first compartment; and an activation assembly carried by the housing, wherein activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly.