METHODS OF TREATING A SUBJECT WITH A COGNITIVE DYSFUNCTION USING SPINAL CORD-DERIVED NEURAL STEM CELLS

摘要

The disclosure relates generally to methods of treating a subject with a cognitive dysfunction by administering to the brain of the subject an effective amount of spinal cord neural stem cells. The present disclosure provides methods for treating a subject with a cognitive dysfunction including, for example, a subject that has received radiotherapy for the treatment of a primary or secondary brain tumor. Such methods may be useful for treating symptoms resulting from exposure to radiation or symptoms of neurological diseases. In one aspect, the present disclosure provides methods for treating a subject with a cognitive dysfunction, for example, a human, by introducing a therapeutically effective amount of spinal cord-derived neural stem cells to one or more areas of the subject's brain (e.g., hippocampus).