Selection and use of lactic acid bacteria preventing bone loss in mammals

摘要

The present invention comprises a method for selecting lactic acid bacterial strains effective for preventing bone loss in humans and strains that have been selected according to the presented method. The selection method is based on the strains capability of reestablishing an altered microbial community to normal and/or harboring at least one of four specific SNPs (C in base pair 271 391, G in base pair 453 538, G in base pair 529 228, and C in base pair 599 338 relative to the genome of L reuteri JCM 1 1 12).