发明名称 |
COMBINATION THERAPIES FOR MALARIA |
摘要 |
The present disclosure provides methods for treating or preventing malaria by administration of a protein kinase inhibitor and optionally one or both of a further protein kinase inhibitor and an antimalarial drug to a mammalian subject infected with or at risk of exposure to Plasmodium sp. In some aspects, the therapeutic and prophylactic regimens of the present disclosure are effective in reducing parasite development in mosquitos feeding on recipients of the regimens. Additionally, the present disclosure provides methods for screening candidate antimalarial agents. |
申请公布号 |
WO2015006752(A1) |
申请公布日期 |
2015.01.15 |
申请号 |
WO2014US46440 |
申请日期 |
2014.07.11 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LUCKHART, SHIRLEY;GIULIVI, CECILIA |
分类号 |
A61K31/55;A61P33/06;C12Q1/37 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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