| 摘要 |
Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections A method and a composition for treatment of pulmonary bacterial infections caused by gram negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumonia, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenza, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam lysinate delivered as an aerosol or dry formulation. A process for manufacturing aztreonam lysinate. |
