INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING OCULAR CONDITIONS

摘要

PROBLEM TO BE SOLVED: To provide biocompatible, bioerodible sustained release implants and microspheres for intracameral or anterior vitreal placement for treating ocular hypertension.SOLUTION: A method for treating elevated intraocular pressure comprises the step of intracameral or anterior vitreal administration, to a patient with elevated intraocular pressure (IOP), of a sustained release implant comprising an anti-hypertensive agent and a biodegradable polymer. The implant comprises about 10 mass percent to about 50 mass percent of the anti-hypertensive agent and about 50 mass percent to about 90 mass percent of the biodegradable polymer. The implant releases therapeutically effective amounts of the anti-hypertensive for a period of time between about 10 days and about 120 days.