发明名称 |
METHODS AND COMPOSITIONS FOR TREATING POST-OPERATIVE PAIN COMPRISING A LOCAL ANESTHETIC |
摘要 |
The present invention is directed to an implantable drug depot useful for reducing, preventing or treating post-operative pain in a patient in need of such treatment, the implantable drug depot comprising a polymer and a therapeutically effective amount of a local anesthetic or pharmaceutically acceptable salt thereof, wherein the drug depot is implantable at a site beneath the skin to reduce, prevent or treat post-operative pain, and the drug depot is capable of releasing (i) a bolus dose of the local anesthetic or pharmaceutically acceptable salt thereof at a site beneath the skin and (ii) a sustained release dose of an effective amount of the local anesthetic or pharmaceutically acceptable salt thereof over a period of at least 4 days. |
申请公布号 |
US2015018390(A1) |
申请公布日期 |
2015.01.15 |
申请号 |
US201414499469 |
申请日期 |
2014.09.29 |
申请人 |
Warsaw Orthopedic, Inc. ;Medtronic, Inc. |
发明人 |
Wohabrebbi Amira;McKay William F.;King Vanja Margareta;Biggs Danielle L.;Shaw Katara;Hobot Christopher;McDonald Phillip Edward |
分类号 |
A61K31/445 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Warsaw IN US |