| 摘要 |
A pipette tip 20 characterised by containing a rigid porous matrix (22), such as a filter disc or frit comprising sintered thermoplastic polymer, on which a ligand, such as an antibody, e.g. immunoglobulin, protein A or protein G, is immobilised, the ligand capable of binding to a protein associated with chromatin. The rigid porous matrix (22) is positioned within the pipette tip 20 such that in use chromatin in a liquid sample passing through the pipette tip 20 is retained by the rigid porous matrix (22). Also disclosed, is a method or kit comprising the pipette tip 20 for performing chromatin immunoprecipitation assay. |
