发明名称 |
PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PREVENTION OF CANCER |
摘要 |
This invention provides an antibody targeting a cancer antigenic protein specifically expressed on the surface of cancer cells and use thereof in a therapeutic and/or preventive agent for cancer. Specifically, this invention provides an antibody or a fragment thereof which has immunological reactivity with a partial CAPRIN-1 polypeptide consisting of the amino acid sequence set forth in SEQ ID NO: 5 or an amino acid sequence having 80% or higher sequence identity to the amino acid sequence, and a pharmaceutical composition for treatment and/or prevention of cancer, comprising the antibody or fragment thereof as an active ingredient. |
申请公布号 |
EP2824114(A1) |
申请公布日期 |
2015.01.14 |
申请号 |
EP20130751164 |
申请日期 |
2013.02.21 |
申请人 |
TORAY INDUSTRIES, INC. |
发明人 |
KOBAYASHI, SHINICHI;OKANO, FUMIYOSHI;SAITO, TAKANORI |
分类号 |
C07K16/30;A61K39/395;A61P35/00;C12N15/09;C12P21/08 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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