| 发明名称 |
NOVEL NICOTINE DNA VACCINES |
| 摘要 |
The present invention provides DNA-nanostructures comprising and at least one targeting moiety, wherein the at least one targeting moiety is linked to the DNA-nanostructure; and wherein the at least one targeting moiety is nicotine or a nicotine analogue. These compounds elicit an immunogenic response in individuals and are useful as vaccines for ameliorating nicotine dependence. |
| 申请公布号 |
US2015017201(A1) |
申请公布日期 |
2015.01.15 |
| 申请号 |
US201414209845 |
申请日期 |
2014.03.13 |
| 申请人 |
Regents of the University of Minnesota ;Arizona Board of Regents, A Body Corporate of the State of Arizona, Acting for and on behalf of Ariz |
发明人 |
Chang Yung;Yan Hao;Hecht Sidney;Pentel Paul;Liu Xiaowei;Maini Rumit |
| 分类号 |
A61K39/385;A61K39/39;A61K39/00 |
主分类号 |
A61K39/385 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound comprising a DNA-nanostructure and at least one targeting moiety,
wherein the at least one targeting moiety is linked to the DNA-nanostructure; and wherein the at least one targeting moiety is nicotine or an analogue thereof. |
| 地址 |
Minneapolis MN US |
