发明名称 |
Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods |
摘要 |
The invention provides a polypeptide containing at least one IgG Fc region, said polypeptide having a higher anti-inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide. |
申请公布号 |
EP2815768(A3) |
申请公布日期 |
2015.01.14 |
申请号 |
EP20140183260 |
申请日期 |
2007.04.03 |
申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
RAVETCH, JEFFREY V.;KANEKO, YOSHIKATSU;NIMMERJAHN, FALK |
分类号 |
A61K39/395;C07K16/00;C07K16/18;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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