发明名称 |
LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME |
摘要 |
<p>Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed.</p> |
申请公布号 |
EP2822576(A1) |
申请公布日期 |
2015.01.14 |
申请号 |
EP20130749077 |
申请日期 |
2013.02.05 |
申请人 |
OPKO BIOLOGICS LTD |
发明人 |
FIMA, UDI EYAL;HART, GILI |
分类号 |
A61K38/36;A61K38/24;A61P7/04;C07K14/475;C07K14/755 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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