发明名称 |
USE OF ERBB3 INHIBITORS IN THE TREATMENT OF TRIPLE NEGATIVE BREAST CANCER |
摘要 |
<p>Provided are methods of suppressing growth of triple negative breast tumors and basal-like breast tumors by contacting tumor cells with an ErbB3 inhibitor, e.g., an anti-ErbB3 antibody. Also provided are methods for treating triple negative breast cancer or basal-like breast cancer in a patient by administering to the patient an ErbB3 inhibitor, e.g., an anti-ErbB3 antibody. The treatment methods can further comprise selecting a patient having a triple negative breast cancer or basal-like breast cancer and then administering an ErbB3 inhibitor to the patient. The treatment methods also can further comprise administering at least one additional anti-cancer agent to the patient in combination with the ErbB3 inhibitor.</p> |
申请公布号 |
EP2544680(B1) |
申请公布日期 |
2015.01.14 |
申请号 |
EP20110730112 |
申请日期 |
2011.03.11 |
申请人 |
MERRIMACK PHARMACEUTICALS, INC. |
发明人 |
MOYO, VICTOR;GARCIA, GABRIELA |
分类号 |
A61P35/00;A61K31/337;A61K31/517;A61K39/00;A61K39/395;A61K45/06;C07K16/28;C07K16/30;C07K16/32 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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