发明名称 MAMMALIAN TRANSGENESIS BY INTRACYTOPLASMIC SPERM INJECTION
摘要 <p>Coinjection of unfertilized mouse oocytes with sperm heads and exogenous nucleic acid encoding a transgene results in transgene-expressing embryos, reflecting nucleic acid-sperm head association before coinjection. Nonselective transfer to surrogate mothers of embryos resulting from coinjection produced offspring expressing the integrated transgene.</p>
申请公布号 WO2000009674(A1) 申请公布日期 2000.02.24
申请号 US1999018118 申请日期 1999.08.10
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