主权项 |
1. A compound of Formula I, or a pharmaceutically acceptable salt thereof, or a stereoisomer thereof, or a pharmaceutically acceptable salt of the stereoisomer thereof: wherein m is 0 or 1; n is 0, 1, or 2; q is 0 or 1; A is —CH═ or —N═; B1 is —CH2— or —NH—; R6 and R9 are each a hydrogen; or R6 and R9 form a direct bond; each occurrence of R1 and R2 is independently selected from the group consisting of:
(1) C1-C4 alkyl optionally substituted with 1 to 3 halogen atoms, and(2) halogen; each occurrence of R3 is independently selected from the group consisting of:
(1) C1-C4 alkyl optionally substituted with 1 to 3 groups independently selected from:
(a) halogen,(b) —ORa, and(c) a 5- to 6-membered heterocyclic ring with 1 to 4 nitrogen atoms, optionally substituted with 1 to 3 groups independently selected from halogen, C1-C4 alkyl optionally substituted with 1 to 3 halogen atoms,(2) halogen,(3) —ORa,(4) —NRaRb, and(5) a 5- to 6-membered heterocyclic ring with 1 to 4 nitrogen atoms, optionally substituted with 1 to 3 groups independently selected from
(a) C1-C4 alkyl optionally substituted with 1 to 3 halogen atoms,(b) halogen,(c) —ORa, and(d) —NRaRb; and each occurrence of Ra and Rb is independently selected from the group consisting of:
(1) hydrogen, and(2) C1-C4 alkyl optionally substituted with 1 to 3 halogen atoms. |