| 摘要 |
A two-part aqueous composition for treating skin ailments, such as acne vulgaris, includes an acidic part having salicylic acid and an α-hydroxy acid, and an alkaline part having an alkaline nitrite salt. The α-hydroxy acid is preferably glycolic acid, lactic acid, malic acid, mandelic acid or a combination thereof. The alkaline nitrite salt is preferably sodium nitrite. The acidic part and the alkaline part are an acidic aqueous solution and an alkaline aqueous solution, respectively, which may either be mixed with one another then applied to an affected portion of a patient's skin or, alternatively, may be sequentially applied to the affected portion of the patient's skin, preferably within 15 minutes of one another. |
| 主权项 |
1. A method for treating acne vulgaris, comprising the steps of:
formulating an acidic aqueous solution having salicylic acid and an α-hydroxy acid, with said acidic aqueous solution having no lactic acid and no glycolic acid; formulating an alkaline aqueous solution having an alkaline nitrite salt; and, sequentially applying said acidic aqueous solution directly to the portion of the skin of the patient and three minutes to fifteen minutes later applying said alkaline aqueous solution directly to the portion of the skin of the patient to which said acidic aqueous solution has already been applied thereby producing nitrous acid, the activity of which supplements that of said acidic aqueous solution for treating acne vulgaris afflicting the portion of the skin of the patient, wherein the α-hydroxy acid concentration is in the range of from about 0.5% to about 5.0% as calculated upon a combined volume of said acidic aqueous solution and said alkaline aqueous solution. |
