Felbinac-containing transdermally absorbable preparation

摘要

An adhesive patch is a felbinac-containing transdermally absorbable preparation substantially free of a solubilizer for felbinac in a final preparation but still having high releasing of felbinac. The adhesive patch in which lidocaine and felbinac are formulated has the releasing of felbinac without losing the releasing of lidocaine. The felbinac-containing transdermally absorbable adhesive patch contains felbinac as an active component and lidocaine or a pharmaceutically acceptable salt thereof as an absorption promoter. In particular, the content of felbinac is from 0.1% to 10% by weight to the total weight of the drug-containing plaster and the content of lidocaine or the pharmaceutically acceptable salt thereof is from 0.01% to 20% by weight to the total weight of the drug-containing plaster.

主权项

1. A transdermal adhesive patch comprising an adhesive patch base comprising felbinac as an active component and lidocaine or a pharmaceutically acceptable salt thereof as an absorption promoter; wherein
the adhesive patch base is a styrene-isoprene-styrene block copolymer; the felbinac is present in an amount of 0.1% to 10% by weight of the total weight of said adhesive patch base; and the lidocaine or a pharmaceutically acceptable salt thereof is present in an amount of 0.01% to 20% by weight of the total weight of said adhesive patch base.