发明名称 Adsorbent for lymphocyte proliferation inhibitor and treating method
摘要 The invention relates to a porous material for body fluid treatment for promoting lymphocyte proliferation in lymphocyte culture which contains a high-molecular compound having an angle of contact with water within the range of 40 to 98°, and a porous material for body fluid treatment which comprises activated carbon; and also relates to a treatment device wherein the porous material is used; a method for proliferating lymphocytes; a method for producing mammalian lymphocytes; a method for producing a pharmaceutical composition; an additive body fluid to be added to a culture medium on the occasion of lymphocyte culture; a method for treating a disease against which a therapeutic effect is produced by returning extracorporeally activated mammalian lymphocytes into the body; and a method of manufacturing the porous materials for body fluid treatment for promoting the lymphocyte proliferation in lymphocyte culture.
申请公布号 US8932854(B2) 申请公布日期 2015.01.13
申请号 US201012771373 申请日期 2010.04.30
申请人 Kaneka Corporation 发明人 Kobayashi Akira;Yoshida Shinya;Noguchi Katsuo
分类号 C12N5/078;C12N5/02;A61K35/14;A61M1/36;C12N5/0783 主分类号 C12N5/078
代理机构 Novak Druce Connolly Bove + Quigg LLP 代理人 Novak Druce Connolly Bove + Quigg LLP
主权项 1. A method for proliferating lymphocytes which comprises contacting a body fluid with a porous material which contains a polymer having an angle of contact with water within the range of 40° to 98° thereby removing lymphocyte proliferation inhibitor, wherein said polymer does not have a compound selected from the group consisting of amines, alcohols, glycidyl ethers, carboxylic acids and derivatives thereof, acid halides, halides, halogenated silanes, thiols, aldehydes and antibodies immobilized thereon, and adding together the lymphocytes in the body fluid after contacting with said porous material and a lymphocyte culture medium to culture lymphocytes.
地址 Osaka JP