| 发明名称 | Growth factor isoform | ||
| 摘要 | An isolated VEGF polypeptide having anti-angiogenic activity, said polypeptide including the amino acid sequence of SEQ. ID NO. 1, or variants thereof. | ||
| 申请公布号 | US8933211(B2) | 申请公布日期 | 2015.01.13 |
| 申请号 | US201313757221 | 申请日期 | 2013.02.01 |
| 申请人 | University of Bristol | 发明人 | Bates David O.;Harper Steven J. |
| 分类号 | C07H21/04;A61K48/00;C07K14/475;C07K14/52;A61K38/18;C12N15/113 | 主分类号 | C07H21/04 |
| 代理机构 | Nixon Peabody LLP | 代理人 | Nixon Peabody LLP ;Eisenstein Ronald I.;Karttunen Contarino Leena H. |
| 主权项 | 1. An isolated cDNA nucleotide molecule capable of encoding a VEGF polypeptide having anti-angiogenic activity, said polypeptide comprising an amino acid sequence that is at least 95% identical to the C-terminal 165 amino acid sequence from SEQ. ID NO. 17, wherein the polypeptide inhibits pro-angiogenic VEGF receptor activity. | ||
| 地址 | Bristol GB | ||