Use of selective estrogen receptor modulator for joint fusion and other repair or healing of connective tissue

摘要

Methods for facilitating joint immobilization or fusion using selective estrogen receptor modulator (SERM) such as raloxifene are disclosed. The SERM may be administered systemically or locally. In conjunction with SERM, other therapeutic agents such as calcium, vitamin D, bone morphogenetic protein may be administered simultaneously. The method can similarly be applied to facilitate bone repair, bone healing, and connective tissue healing processes in a patient.

主权项

1. A method for the improvement of bone healing, the method comprising: administering locally an effective amount of a composition comprising a selective estrogen receptor modulator (SERM) to a patient, to improve the bone healing process wherein the patient also receives an osteoconductive material.