发明名称 |
CD44V6 peptides as inhibitors of bacterial infections |
摘要 |
A method for treatment of infection with Listeria spp., Plasmodium spp., or Shigella spp. includes administering a peptide or a pharmaceutically acceptable salt of the peptide to an individual in need of treatment for the infection. |
申请公布号 |
US8933017(B2) |
申请公布日期 |
2015.01.13 |
申请号 |
US201213673749 |
申请日期 |
2012.11.09 |
申请人 |
Karlsruher Institut fur Technologie |
发明人 |
Jung Christian;Orian-Rousseau Véronique;Matzke Alexandra;Ponta Helmut |
分类号 |
A61K38/12;A61K38/10;A61K38/04;A61K38/08;C07K7/08;C07K7/00;C07K5/12;A61K38/17;C07K14/705 |
主分类号 |
A61K38/12 |
代理机构 |
Knobbe, Martens, Olson & Bear, LLP |
代理人 |
Knobbe, Martens, Olson & Bear, LLP |
主权项 |
1. A method for treatment of a bacterial infection in an individual comprising:
administering to an individual in need of treatment of bacterial infection a peptide compound comprising the amino acid sequence set forth in amino acids 7 to 11 of SEQ ID NO: 2, or a pharmaceutically acceptable salt of said peptide in an amount of about 0.01 to about 1000 mg of per kg body weight of a subject per day throughout a course of treatment effective to treat the bacterial infection, wherein the bacterial infection is an infection with an intracellular bacterium selected from the group consisting of Listeria spp., Plasmodium spp., and Shigella spp. |
地址 |
Karlsruhe DE |