Redundant tissue closure methods and apparatuses

摘要

A tissue closure device including a tissue eversion apparatus, and a first and a second, redundant closure element that are placed on the external surface of a tissue puncture wound to enhance the efficacy of closure. The first closure element and the second closure element are left resident on the external surface of or in proximity to the tissue puncture wound in order to provide redundancy of closure.

主权项

1. A closure device for closing an opening in a tissue, the closure device comprising:
a tubular member having a proximal end and a distal end region, an exterior surface, and a lumen extending along an entire length of the tubular member; a tissue eversion apparatus configured to form an everted tissue region, the tissue eversion apparatus having a plurality of elongate tissue engaging members disposed within the lumen of the tubular member and deployable therefrom, in a deployed position the elongate tissue engaging members having ends thereof configured to engage the tissue surrounding the opening, and in the deployed position the elongate tissue engaging members curve away from center axes of each of the elongate tissue engaging members thereof in a manner that the ends thereof face away from each other, for approximating and everting edges of the tissue engaged by the elongate tissue engaging members; a first closure element operatively coupled to the tubular member and deliverable therefrom for closing the opening, the first closure element being held in place in the lumen of the tubular member by a retention structure; the first closure element being a cincture element having a first size and a second size that is smaller than the first size; the first size being configured to surround a portion of the everted tissue region around the opening; and the second size being configured to capture the portion of the everted tissue region and close the opening when the cincture element is transitioned from the first size towards the second size.