Method and apparatus for repairing vascular abnormalities and/or other body lumen abnormalities using an endoluminal approach and a flowable forming material

摘要

Apparatus and method for repairing an abnormality in the wall of a body lumen, the method comprising isolating the abnormality in the wall of the body lumen from flow in the body lumen; positioning flowable forming material adjacent to the abnormality in the wall of the body lumen; and transforming the flowable forming material into a substantially stationary state so as to repair the abnormality in the wall of the body lumen, and the apparatus comprising a supply of flowable forming material; zone isolation apparatus for isolating the abnormality in the wall of the body lumen from flow in the body lumen; and positioning apparatus for positioning the flowable forming material adjacent to the abnormality in the wall of the body lumen so as to repair the abnormality in the wall of the body lumen.

主权项

1. A method for repairing an abnormality in the wall of a body lumen, the method comprising:
providing an access system comprising:
an erectable proximal isolation barrier capable of making a sealing engagement with the wall of the body lumen;an erectable distal isolation barrier capable of making a sealing engagement with the wall of the body lumen, the erectable distal isolation barrier being formed separately from the erectable proximal isolation barrier;a bypass channel secured to, and extending between, the proximal isolation barrier and the distal isolation barrier, the bypass channel comprising a lumen communicating with the region of the body lumen proximal to the proximal isolation barrier and with the region of the body lumen distal to the distal isolation barrier so that fluid can be passed from the region of the body lumen proximal to the proximal isolation barrier through the bypass channel and to the region of the body lumen distal to the distal isolation barrier;a working catheter passing through the proximal isolation barrier and into the region between the proximal isolation barrier and the distal isolation barrier, the working catheter providing a central lumen for providing access to the wall of the body lumen between the proximal isolation barrier and the distal isolation barrier;a supply catheter extendible out of the working catheter; anda mold structure extending between the proximal isolation barrier and the distal isolation barrier, the mold structure comprising a substantially continuous film; isolating the abnormality in the wall of the body lumen from fluid flowing through the body lumen, while still allowing fluid to flow between the region of the body lumen proximal to the proximal isolation barrier and the region of the body lumen distal to the distal isolation barrier, by positioning the access system within the body lumen and erecting the distal isolation barrier and the proximal isolation barrier so that the proximal isolation barrier makes a sealing engagement with the wall of the body lumen proximal to the abnormality, the distal isolation barrier makes a sealing engagement with the wall of the body lumen distal to the abnormality, and the bypass channel provides the only fluid flow between the region of the body lumen proximal to the proximal isolation barrier and the region of the body lumen distal to the distal isolation barrier, with the mold structure isolating the abnormality from the region of the body lumen between the proximal isolation barrier and the distal isolation barrier, and with the mold structure following a cylindrical geometry so as to conform to the adjacent body lumen; positioning flowable forming material adjacent to the abnormality in the wall of the body lumen by advancing the supply catheter out of the working catheter and through the mold structure and by passing the flowable forming material into the space between the wall of the body lumen and the mold structure; and transforming the flowable forming material into a substantially stationary state so as to repair the abnormality in the wall of the body lumen.