| 发明名称 | Crystallization method and bioavailability | ||
| 摘要 | Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans. | ||
| 申请公布号 | US8933057(B2) | 申请公布日期 | 2015.01.13 |
| 申请号 | US201313766034 | 申请日期 | 2013.02.13 |
| 申请人 | Thar Pharmaceuticals, Inc. | 发明人 | Hanna Mazen;Shan Ning;Cheney Miranda L.;Weyna David R.;Houck Raymond K. |
| 分类号 | A61K31/675;A61K31/20;A61K9/14;A61K9/20;C07F9/6506;A61K31/375;A61K47/48 | 主分类号 | A61K31/675 |
| 代理机构 | J.A. Lindeman & Co., PLLC | 代理人 | J.A. Lindeman & Co., PLLC |
| 主权项 | 1. A molecular complex comprising zoledronic acid and glycine, wherein the molecular complex is a solid. | ||
| 地址 | Pittsburgh PA US | ||