发明名称 Method and system for purifying charged radioisotopes
摘要 The present invention provides a simple and inexpensive method for removing metal and other impurities in a radioisotope solution. The invention further includes the development of a new parent/daughter generator system for collecting the daughter isotope in a concentrated solution.
申请公布号 US8932876(B2) 申请公布日期 2015.01.13
申请号 US200912454003 申请日期 2009.05.11
申请人 The Curators of the University of Missouri 发明人 Cutler Cathy Sue;Ehrhardt Gary John;Engelbrecht Hendrik Petrus;Day Delbert E.
分类号 B01D15/36;G21H5/02;G21G1/00;A61K51/00;G21G4/08 主分类号 B01D15/36
代理机构 Stinson Leonard Street LLP 代理人 Stinson Leonard Street LLP
主权项 1. A method for generating an eluate containing daughter isotope in ionic form from a parent/daughter isotope solution, said method comprising: a) providing an acid-treated glass adsorbent column, b) providing a loading solution by adjusting the isotope solution to a pH of above about 4.0, (c) adding N-methylglucamine to the loading solution to change the dielectric properties of the loading solution and increase the activity coefficient of the daughter isotope relative to the to the parent isotope to increase selective adsorption of the daughter isotope onto the column over the parent isotope, d) loading the column with the loading solution, e) rinsing the loaded column with water to elute off the parent isotope, and f) eluting the daughter isotope in a solution by rinsing the column with an acid solution.
地址 Columbia MO US