发明名称 Novel aminopyrimidine derivatives as PLK1 inhibitors
摘要 <p>The present invention relates to a compound represented by Formula [I]: or a pharmaceutically acceptable salt or ester thereof, wherein R 1 and R 2 , which may be the same or different, are each a hydrogen atom, a lower alkyl group, a cycloalkyl group, or the like; R 3 and R 4 , which may be the same or different, are each a hydrogen atom, a lower alkyl group, NR a R b , a phenyl group, a lower alkyl group substituted with a phenyl group, a 4- to 7-membered aliphatic heterocyclic group, a lower alkyl group substituted with a 4- to 7-membered aliphatic heterocyclic group, a 5- or 6-membered aromatic heterocyclic group, a lower alkyl group substituted with a 5- or 6-membered aromatic heterocyclic group, or the like; and R 5 is a hydrogen atom, a cyano group, a halogen atom, or a lower alkyl group.</p>
申请公布号 KR101481388(B1) 申请公布日期 2015.01.12
申请号 KR20097013324 申请日期 2007.12.20
申请人 发明人
分类号 A61K31/506;A61P35/00;A61P43/00;C07D471/04 主分类号 A61K31/506
代理机构 代理人
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