| 发明名称 |
Methods and Compositions for Producing Vitamin K Dependent Proteins |
| 摘要 |
The present invention relates to methods and compositions for improving the productivity of recombinant vitamin K dependent protein expression in host cells. |
| 申请公布号 |
US2015010997(A1) |
申请公布日期 |
2015.01.08 |
| 申请号 |
US201414490244 |
申请日期 |
2014.09.18 |
| 申请人 |
The University of North Carolina at Chapel Hill |
发明人 |
Stafford Darrel W.;Li Tao |
| 分类号 |
C12N9/04 |
主分类号 |
C12N9/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A host cell comprising a recombinant nucleic acid coding for a vitamin K epoxide reductase (VKOR) or a functionally active derivative thereof, and a recombinant nucleic acid coding for a vitamin K dependent protein or a functionally active derivative thereof, wherein both the recombinant VKOR and the recombinant Vitamin K dependent protein are expressed in said host cell. |
| 地址 |
Chapel Hill NC US |
