METHODS OF TREATMENT FOR GUILLAIN-BARRE SYNDROME

摘要

This invention relates generally to methods of treatment for Guillain-Barre' Syndrome (GBS) and, more specifically, to methods involving the inhibition of the classical pathway of complement activation. Certain aspects of the present disclosure are directed to methods of treating Guillain-Barre' syndrome (GBS) that include inhibiting the classical pathway of complement activation by neutralizing the complement factors C1q, C1r, or C1s, e.g., through the administration of antibodies, such as monoclonal, chimeric, humanized antibodies, antibody fragments, etc., which bind to one or more of these complement factors.