Method for extracting treatment ingredients for gastrointestinal diseases from bark of liriodendron tulipifera

摘要

The present invention relates to a method for extracting treatment ingredients for gastrointestinal diseases from the bark of Liriodendron tulipifera, the treatment ingredients containing epitulipinolide and costunolide as active ingredients, and to a therapeutic agent for gastrointestinal diseases, containing epitulipinolide and costunolide extracted using said method.

主权项

1. A process for preparing the extract from the bark of Liriodendron tulipifera comprising the steps of:
1) mixing 1 wt part of chopped and dried bark of Liriodendron tulipifera with from 2 to 20 wt part of ethyl acetate or dichloromethane; and 2) extracting and concentrating said mixture for from 1 to 4 days at from 15 to 50° C., wherein said extract comprises from 0.1 to 10 wt % of epitulipinolide and costunolide, said extraction is made by at least one selected from enfleurage, percolation, ultra sonic, maceration or reflux.